PACE Talks
The role of HDL in atherosclerosis
News - Dec. 21, 2011 Prof. John Chapman (Paris, France) and dr. Kees Hovingh (Amsterdam, The Netherlands) discuss about the role of HDL in atherosclerosis.'I think studying families with carries of mutations in those pivotal genes is only one model', Hovingh tells about the relationship between functional mutations in the major genes involved in HDL metabolism and cardiovascular risk. For example, mutations in LCAT, ABCA1, and ApoA-1 studied in terms of surrogate markers. In his view, ApoA-1 is one of the best targets of atherosclerosis. 'I think we are at a watershed in this field', Chapman adds. 'We really need in the international community to move together to try to define the most informative experimental systems that we should be using for the future.' Topics discussed in this PACE talk:
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View the slides
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