Physicians' Academy for Cardiovascular Education

Epigenetics: A closer look at BET inhibition

Sep. 5, 2016

This video shows the potential mechanism of BET bromodomain inhibition which is an epigenetic mechanism that can regulate disease-causing genes. Apabetalone is the first and only BET inhibitor selective for the second bromodomain (BD2) within the BET protein called BRD4. This selective inhibition of apabetalone on BD2 produces a specific set of biological effects with potentially important benefits for patients with diseases such as cardiovascular disease (CVD), diabetes mellitus (DM)

This video is provided as an educational service by Resverlogix corp.

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