Physicians' Academy for Cardiovascular Education

LDL-c as target in cardiology: The road towards lower targets

Expert Meeting on LDL-c & PCSK9 inhibition in high CV risk patients

5' education - Jan. 22, 2019 - John Kastelein, Chris Packard - Online CME

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  • What do we need to understand about the biology and metabolism of the LDL-particle? 00:35
  • Does it matter how LDL-c targets are achieved? 02:36
  • Lowering of LDL-c by drugs accelerating LDL clearance along the LDL pathway 03:50
  • Is the side effect profile of these drugs beneficial enough to warrant use in large populations? 05:10

Educational information

This video was recorded during an expert meeting among cardiologists and internists, focussing on the topic of 'LDL-c & PCSK9 inhibition in high CV risk patients - Balancing Science, Guidelines and Daily Cardiology Practice'.

The objectives of the meeting were to:

Other topics covered in this series

Other lectures part of this educational series are:


Prof. John J.P. Kastelein, MD, internist, Professor of Medicine, Department of Vascular Medicine; Strategic Chair of Genetics of Cardiovascular Disease at the Amsterdam University Medical Centers (AUMC) of the University of Amsterdam, The Netherlands

Prof. Chris Packard, Research and Development Director, NHS Greater Glasgow & Clyde Health Board; Honorary professor of vascular biochemistry, University of Glasgow, Scotland, United Kingdom


This recording was independently developed under auspices of PACE-cme. The views expressed in this recording are those of the individual presenters and do not necessarily reflect the views of PACE-cme.

Funding for the Expert Meeting was provided by an unrestricted educational grant from Amgen. The sponsor did not attend and influence the video recording.


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The information and data provided in this program were updated and correct at the time of the program development, but may be subject to change.

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