ACC scientific statement on antiplatelet therapy in ASCVD
01/07/2026
The American College of Cardiology (ACC) has published a new scientific statement on the use of antiplatelet therapy in ASCVD.
Published in J Am Coll Cardiol., the statement reviews contemporary evidence on antiplatelet therapy in ASCVD and provides practical recommendations to support individualized treatment decisions across a range of clinical settings. It compares recommendations from current ACC/AHA and ESC guidelines, summarizes findings from pivotal clinical trials, and discusses antiplatelet strategies for patients with differing ischemic and bleeding risks, those undergoing surgery, and those requiring concomitant antithrombotic therapy. The statement also addresses long-term management, including treatment monitoring and adherence.