Atrial Fibrillation

Both baseline and lifetime alcohol intake were inversely associated with the risk of non-fatal CHD, and positively associated with the risk of ischemic and hemorrhagic stroke.

Introduction and Methods

Patients with a transient ischemic attack or minor stroke had a sustained elevated risk of CV events up to 5 years after the first event, and approximately half of these events occurred after the first year.

Introduction and metho...

Compared with placebo, alogliptin did not increase CV risk in type 2 diabetic patients up to 6 months after an ACS, or later.

Rivaroxaban therapy is not beneficial for the prevention of stroke recurrence and associated with a higher risk of bleeding compared to aspirin in patients with embolic stroke of undetermined source.

Introduction and method...

The European Commission (EC) has approved the use of evolocumab in patients with established atherosclerotic CVD (MI, stroke, PAD) to reduce CV risk.

Approval of evolocumab by the European Commission (EC) is now in place for patients with established atherosclerotic CVD (myocardial infarction [MI], stroke, or peripheral arterial ...

Patients with hypertension with low platelet counts and high total homocysteine levels, which may promote platelet adherence, had the highest risk of first stroke, and this risk was reduced with folic acid treatment.

Introduction and methods

The role of platelets in...

Patients with T2DM and atherosclerotic poly-vascular disease have a higher CV risk than patients with single vascular disease, and in both groups liraglutide consistently reduced major CV outcomes.

In a retrospective analysis of a healthcare cost and utilization database, cannabis use was associated with a lower AF risk in hospitalized heart failure patients.

Individuals with at least one laboratory-confirmed respiratory infection had a higher risk of MI or stroke, in particular when infected with S. pneumoniae or influenza virus.

Different measures of fitness and physical activity were inversely associated with future CVD events and all-cause death, also in individuals with a high genetic CVD predisposition.

In the AXAFA-AFNET 5 trial, continuous apixaban therapy was non-inferior to continuous VKA treatment in terms of stroke, bleedings, cognitive function and MRI-detected acute brain lesions.

Introduction and m...

In a large prospective study, risk of all-cause mortality increases above 100 g alcohol per week, and positive associations with alcohol intake were seen mostly for stroke and HF, as opposed to MI.

Visit-to-visit variability in fasting measurements of HDL-c, TG, and LDL-c is predictive of coronary events, CV events, and TG and LDL-c variability is also predictive of incident diabetes.

Introduction and methods

Lon...

Neither FH mutations, nor high LDL-c levels were associated with an increased risk of ischemic stroke, with the exception of patients with a history of ischemic heart disease.

Mendelian randomization study suggests that lowering LDL affects large artery atherosclerosis, but not small artery occlusion or cardioembolic stroke, while increasing HDL may benefit small artery disease.

Introduction a...

Incident atrial fibrillation (AF) is associated with both greater cognitive decline and increased risk of dementia compared with individuals without AF, independent of clinical ischemic stroke.